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A microfluidic transistor for automatic control of liquids.
Gopinathan KA, Mishra A, Mutlu BR, Edd JF, Toner M. Gopinathan KA, et al. Nature. 2023 Oct;622(7984):735-741. doi: 10.1038/s41586-023-06517-3. Epub 2023 Oct 25. Nature. 2023. PMID: 37880436 Free PMC article.
Here we exploit the fluidic phenomenon of flow limitation(16) to develop a microfluidic element capable of proportional amplification with flow-pressure characteristics completely analogous to the current-voltage characteristics of the electronic transistor. …
Here we exploit the fluidic phenomenon of flow limitation(16) to develop a microfluidic element capable of proportional amplification …
A Microfluidic Transistor for Liquid Signal Processing.
Gopinathan KA, Mishra A, Mutlu BR, Edd JF, Toner M. Gopinathan KA, et al. bioRxiv [Preprint]. 2023 Jun 2:2023.05.31.543146. doi: 10.1101/2023.05.31.543146. bioRxiv. 2023. PMID: 37398240 Free PMC article. Preprint.
Prior works on creating a microfluidic analogue to the electronic transistor (12-14) could not replicate the transistor's saturation behavior, which is crucial to perform analog amplification (15) and is fundamental to modern circuit design (16) . Here we exp …
Prior works on creating a microfluidic analogue to the electronic transistor (12-14) could not replicate the transistor's satu …
A novel sweet taste cell-based sensor.
Wang TH, Hui GH, Deng SP. Wang TH, et al. Biosens Bioelectron. 2010 Oct 15;26(2):929-34. doi: 10.1016/j.bios.2010.06.049. Epub 2010 Jul 3. Biosens Bioelectron. 2010. PMID: 20691579
The human colorectal carcinoma NCI-H716 cell lines, which express alpha-gustducin and sweet taste receptor T1R1/T1R3, are cultured on the carbon screen-printed electrode with the pre-coated poly-L-ornithine and lamimin for adhesion in extracellular matrix. The electrode is placed …
The human colorectal carcinoma NCI-H716 cell lines, which express alpha-gustducin and sweet taste receptor T1R1/T1R3, are cultured on the ca …
Ensemble analysis of angiogenic growth in three-dimensional microfluidic cell cultures.
Farahat WA, Wood LB, Zervantonakis IK, Schor A, Ong S, Neal D, Kamm RD, Asada HH. Farahat WA, et al. PLoS One. 2012;7(5):e37333. doi: 10.1371/journal.pone.0037333. Epub 2012 May 25. PLoS One. 2012. PMID: 22662145 Free PMC article.
We demonstrate ensemble three-dimensional cell cultures and quantitative analysis of angiogenic growth from uniform endothelial monolayers. Our approach combines two key elements: a micro-fluidic assay that enables parallelized angiogenic growth instances subject to common …
We demonstrate ensemble three-dimensional cell cultures and quantitative analysis of angiogenic growth from uniform endothelial monolayers. …